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An inducer of ferroptosis; inhibits glutamate release in human CCF-STTG1 astrocytoma cells (IC50 = 30 nM), indicating inhibition of the system xc- cystine/glutamate transporter; increases production of lipid ROS in SUDHL6 DLBCL cells in a concentration-dependent manner, as well as reduces GSH levels in these cells (IC50 = 34 nM); inhibits the growth of HT-1080 fibrosarcoma cells (GI50 = 310 nM) as well as HRASG12V-overexpressing BJeLR cells (IC50 = 3 nM); reduces tumor growth in an SUDHL6 mouse xenograft model at 23 and 40 mg/kg
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More
An intermediate in the synthesis of ursodeoxycholic acid by intestinal bacteria in humans; increases the bile flow rate and the concentration of bile bicarbonate in rats via venous infusion at 1.2 µmol/min per 100 g body weight; levels are decreased in rat feces in a model of adenine-induced chronic renal failure; fecal levels are also reduced in patients with liver cirrhosis or hepatocellular carcinoma
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More
The Rapid Response™ Multi-Drug One Step Cup is an easy-to-use, one-step solution for drug screening that can simultaneously detect multiple drugs in urine samples. This format is a great alternative to the industry's complicated testing processes and is available with and without adulterant tests. It has a longer detection window than saliva tests and provides results in 5 minutes. This product is also available with an option of built-in Specimen Validity/Adulteration Test Strips. (12.26) - AMP1000, BUP10, BZO300, COC300, EDDP100, ETG500, FYL10, MDMA500, MET1000, MOP300, OXY100, THC50 + Cre/SG/pH
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More
An intermediate in the synthesis of ursodeoxycholic acid by intestinal bacteria in humans; increases the bile flow rate and the concentration of bile bicarbonate in rats via venous infusion at 1.2 µmol/min per 100 g body weight; levels are decreased in rat feces in a model of adenine-induced chronic renal failure; fecal levels are also reduced in patients with liver cirrhosis or hepatocellular carcinoma
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More
Pyruvate dehydrogenase (PDH) Enzyme Activity Dipstick Assay Kit is an immunoassay kit for the detection of Pyruvate dehydrogenase (PDH) Enzyme Activity in Mouse, Rat, Cow, Human, Pig in Cell culture extracts, Tissue samples.
An inducer of ferroptosis; inhibits glutamate release in human CCF-STTG1 astrocytoma cells (IC50 = 30 nM), indicating inhibition of the system xc- cystine/glutamate transporter; increases production of lipid ROS in SUDHL6 DLBCL cells in a concentration-dependent manner, as well as reduces GSH levels in these cells (IC50 = 34 nM); inhibits the growth of HT-1080 fibrosarcoma cells (GI50 = 310 nM) as well as HRASG12V-overexpressing BJeLR cells (IC50 = 3 nM); reduces tumor growth in an SUDHL6 mouse xenograft model at 23 and 40 mg/kg
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More